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The bearer of bad news


bros

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Chemo is tiring.

 

It's been nine years, but....yes, I seem to remember. :/ Those moments when you're irrationally angry at the people who care the most are lots of fun, too.

 

Hang in there.

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It's been nine years, but....yes, I seem to remember. :/ Those moments when you're irrationally angry at the people who care the most are lots of fun, too.

 

Hang in there.

 

Prednisone is causing none of the side effects we wanted - like increased appetite, which sucks - down to 104 lbs - was 111 in april (though I think the scale is off by 2 pounds, so I was probably 109 in april, 102 now)

 

Good luck, bros. We're behind you.

 

Yay!

 

Thoughts and prayers and Godspeed on recovery...do you take natural cures also? Turmeric, garlic, vita C and D, etc. Also Cannibus?

 

No natural stuff, other than the laxative if I need it, that's like some plant stuff in a pill from walgreens idk

 

I wish I could do MMJ - it's $600 an oz in my state because of our rotund governor.

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  • 3 weeks later...

I've read a lot of research on strong THC/CBD Cannabis extracts and other cannabinoids being able to both stop the spread cancer and even cure it in some cases. Including success stories, so its not just limited to lab research. The success varies depending on the type of cancer, but it definitely beats doing chemo in my opinion. However in combination with Chemo, it might work better and help with many of the negative side effects of chemo. Its definitely worth researching if you have cancer. With many states legalizing medical marijuana and some fully legalizing it, paying those states a visit may be worthwhile.

 

Cannabinoids, Endocannabinoids and Cancer http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366283/
 
Many laboratories have proposed that cannabinoids and endocannabinoids directly inhibit tumor growth in vitro and in animal tumor models through several different pathways. The inhibition of tumor growth and progression of several types of cancers including glioma, glioblastoma, breast cancer, prostate cancer, thyroid cancer, colon carcinoma, leukemia, and lymphoid tumors have been demonstrated by natural and synthetic cannabinoids, endocannabinoids, endocannabinoid analogs, endocannabinoid transport inhibitors, and endocannabinoid degradation inhibitors. Several different mechanisms have been implicated in the anti-tumorigenic actions of endocannabinoids and include cytotoxic or cytostatic effects, apoptosis induction, and anti-metastatic effects such as inhibition of neo-angiogenesis and tumor cell migration [22]. These effects are dependent on CB1, CB2, transient receptor potential vanilloid type 1 (TRPV1), or are receptor-independent based on the cannabinoid or endocannabinoid and the tissue or tumor cell.
 

Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival. http://www.ncbi.nlm.nih.gov/pubmed/20053780

The cannabinoid 1 (CB(1)) and cannabinoid 2 (CB(2)) receptor agonist Delta(9)-tetrahydrocannabinol (THC) has been shown to be a broad-range inhibitor of cancer in culture and in vivo, and is currently being used in a clinical trial for the treatment of glioblastoma. It has been suggested that other plant-derived cannabinoids, which do not interact efficiently with CB(1) and CB(2) receptors, can modulate the actions of Delta(9)-THC. There are conflicting reports, however, as to what extent other cannabinoids can modulate Delta(9)-THC activity, and most importantly, it is not clear whether other cannabinoid compounds can either potentiate or inhibit the actions of Delta(9)-THC. We therefore tested cannabidiol, the second most abundant plant-derived cannabinoid, in combination with Delta(9)-THC. In the U251 and SF126 glioblastoma cell lines, Delta(9)-THC and cannabidiol acted synergistically to inhibit cell proliferation. The treatment of glioblastoma cells with both compounds led to significant modulations of the cell cycle and induction of reactive oxygen species and apoptosis as well as specific modulations of extracellular signal-regulated kinase and caspase activities. These specific changes were not observed with either compound individually, indicating that the signal transduction pathways affected by the combination treatment were unique. Our results suggest that the addition of cannabidiol to Delta(9)-THC may improve the overall effectiveness of Delta(9)-THC in the treatment of glioblastoma in cancer patients.

A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. http://www.ncbi.nlm.nih.gov/pubmed/20053780

Delta(9)-Tetrahydrocannabinol (THC) and other cannabinoids inhibit tumour growth and angiogenesis in animal models, so their potential application as antitumoral drugs has been suggested. However, the antitumoral effect of cannabinoids has never been tested in humans. Here we report the first clinical study aimed at assessing cannabinoid antitumoral action, specifically a pilot phase I trial in which nine patients with recurrent glioblastoma multiforme were administered THC intratumoraly. The patients had previously failed standard therapy (surgery and radiotherapy) and had clear evidence of tumour progression. The primary end point of the study was to determine the safety of intracranial THC administration. We also evaluated THC action on the length of survival and various tumour-cell parameters. A dose escalation regimen for THC administration was assessed. Cannabinoid delivery was safe and could be achieved without overt psychoactive effects. Median survival of the cohort from the beginning of cannabinoid administration was 24 weeks (95% confidence interval: 15-33). Delta(9)-Tetrahydrocannabinol inhibited tumour-cell proliferation in vitro and decreased tumour-cell Ki67 immunostaining when administered to two patients. The fair safety profile of THC, together with its possible antiproliferative action on tumour cells reported here and in other studies, may set the basis for future trials aimed at evaluating the potential antitumoral activity of cannabinoids.
 

Cannabis Extract Medicine: Successfully Treating Children for Cancer and Epilepsy by Justin Kander http://www.unitedpatientsgroup.com/blog/2014/03/24/cannabis-extract-medicine-successfully-treating-children-for-cancer-and-epilepsy-by-justin-kander/

 

THC is also an integral component of treating cancer.  Both THC and CBD kill cancer cells, and even work synergistically to inhibit cancer through multiple pathways.  However, high-THC oils have historically been more utilized to treat cancer, and there are few cases where high-CBD treatment alone had a significant impact on cancer.  Many parents are using CBD as an adjunct therapy to high-THC oils, both to mitigate the psychoactivity of THC and benefit from the synergy of the two primary cannabinoids.
A growing number of children are experiencing remarkable healing through the use of cannabis extracts.  One of the first children to raise awareness of extract effectiveness for kids was Cash Hyde.  Cash was diagnosed with a Stage IV brain tumor on May 3rd, 2010, and his prognosis was very poor.

Pharmaceuticals and chemotherapy put Cash in the ICU for two weeks.  Cash’s parents soon learned that cannabis oil could potentially fight cancer, and Mike Hyde began secretly giving Cash oil through his feeding tube.  Almost instant improvements were observed, and within two weeks, Cash was feeling much better and was off eight medications.  In January 2011, Cash was declared cancer free.

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Christie will be gone sooner rather than later. Sweeney and Fulop are a lot better on this issue once one of them get elected.

 

It will be nice when Christie is gone. Hopefully a Dem gets elected. Or at least someone who doesn't enjoy screwing the unions gets elected.

Edited by bros2
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My annual review of forum politicking has brought me to this. I've read through your blog a bit, and am taken aback by your levity and bravery when faced with this adversity. Strength and my best wishes to you in your recovery - I will be keeping an active eye on your blog. 

 

Take Care,

Celtic

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  • 2 weeks later...

My annual review of forum politicking has brought me to this. I've read through your blog a bit, and am taken aback by your levity and bravery when faced with this adversity. Strength and my best wishes to you in your recovery - I will be keeping an active eye on your blog. 

 

Take Care,

Celtic

 

I don't really see an alternative way to approach it - people who approach it all grumpy just get sad and annoyed. I have it good - I have a great medical team, a good support system, and most importantly insurance that is paying for everything.

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I am rarely in game for long, and more rarely come to the forums. Since the game seems to be down, I thought I would come along here and see what was up. Happened onto this thread. I'm sorry you're going through this, but I applaud your attitude.  The battle is rough, but it seems you're luckier than most in that you don't have the aggressive form.   I'm sending positive vibes your way.  Nutrition, positive attitude, and the right medical team will get you through this.  Sending an e-hug with those positive vibes. Let us have an update soon?

 

Reyne

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I am rarely in game for long, and more rarely come to the forums. Since the game seems to be down, I thought I would come along here and see what was up. Happened onto this thread. I'm sorry you're going through this, but I applaud your attitude.  The battle is rough, but it seems you're luckier than most in that you don't have the aggressive form.   I'm sending positive vibes your way.  Nutrition, positive attitude, and the right medical team will get you through this.  Sending an e-hug with those positive vibes. Let us have an update soon?

 

Reyne

 

The aggressive form of what I have is even rarer than the indolent & non-aggressive form.

 

Updates are on the blog. Stopped taking the prednisone. Tired from chemo today.

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I had my own bout with cancer (a form of Hodgkin's Lymphoma) four years ago. I didn't need chemo since it was still localized enough for radiation therapy when they diagnosed me. Hopefully, yours will go into remission sooner rather than later. I'm rooting for you!

 

About your dog, if your dad will stop yelling and cursing at her, she'll warm up to him a lot faster.

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  • 2 weeks later...

I am pretty sure you can get prescribed Marinol there at least, it's quite expensive though.

 

o/ bros

 

Insurance will pay for whatever - i've heard Marinol makes you feel rather bad, compared to the upsides.

 

 

I had my own bout with cancer (a form of Hodgkin's Lymphoma) four years ago. I didn't need chemo since it was still localized enough for radiation therapy when they diagnosed me. Hopefully, yours will go into remission sooner rather than later. I'm rooting for you!

 

About your dog, if your dad will stop yelling and cursing at her, she'll warm up to him a lot faster.

 

It would be nice if it went into remission sooner rather than later. NYC oncologist would like the numbers a bit better, he is considering changing the course of treatment. No tumors with mine.

 

She also hates men in general, minus me and my brother.

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Insurance will pay for whatever - i've heard Marinol makes you feel rather bad, compared to the upsides.

 

 

I assume you're not in one of the 23 (?) states that allow medical marijuana? Marinol actually has more side effects than the real thing.

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I assume you're not in one of the 23 (?) states that allow medical marijuana? Marinol actually has more side effects than the real thing.

 

I am in a state that allows medical marijuana - but only a few doctors that went through a length approval process by the state can prescribe it. By prescribing it, they agree to take over treatment for the condition.

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